·       Benign peripheral nerve sheath tumor composed of a mixture of Schwann cells, perineural cells, and fibroblasts, as well as cells with intermediate features.·       In contrast to schwannoma, neurofibromas grow in a permeative fashion and overrun myelinated and unmyelinated fibers of the parent nerve.

·       Who grade I

·       Common tumors, usually solitary/sporadic lesions.

·       Five distinct forms

·       Localized cutaneous neurofibroma

·       Painless, freely movable

·       Diffuse cutaneous neurofibroma

·       Localized intraneural neurofibroma

·       Plexiform intraneural neurofibroma

·       Massive soft tissue variant.

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Ray Jurewicz
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